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Proline-dependent and basophilic kinases phosphorylate human TRPC6 at serine 14 to control channel activity through increased membrane expression., Hagmann H, Mangold N, Rinschen MM, Koenig T, Kunzelmann K, Schermer B, Benzing T, Brinkkoetter PT., FASEB J. January 1, 2018; 32 (1): 208-219.
Proteomic analysis of postsynaptic proteins in regions of the human neocortex., Roy M, Sorokina O, Skene N, Simonnet C, Mazzo F, Zwart R, Sher E, Smith C, Armstrong JD, Grant SGN., Nat Neurosci. January 1, 2018; 21 (1): 130-138.
Postmitotic nuclear pore assembly proceeds by radial dilation of small membrane openings., Otsuka S, Steyer AM, Schorb M, Hériché JK, Hossain MJ, Sethi S, Kueblbeck M, Schwab Y, Beck M, Ellenberg J., Nat Struct Mol Biol. January 1, 2018; 25 (1): 21-28.
Photocontrol of the Hv1 Proton Channel., Rennhack A, Grahn E, Kaupp UB, Berger TK., ACS Chem Biol. December 15, 2017; 12 (12): 2952-2957.
Proteomics of phosphorylation and protein dynamics during fertilization and meiotic exit in the Xenopus egg., Presler M, Van Itallie E, Klein AM, Kunz R, Coughlin ML, Peshkin L, Gygi SP, Wühr M, Kirschner MW., Proc Natl Acad Sci U S A. December 12, 2017; 114 (50): E10838-E10847.
Permeant-specific gating of connexin 30 hemichannels., Nielsen BS, Alstrom JS, Nicholson BJ, Nielsen MS, MacAulay N., J Biol Chem. December 8, 2017; 292 (49): 19999-20009.
Preclinical Characterization of (R)-3-((3S,4S)-3-fluoro-4-(4-hydroxyphenyl)piperidin-1-yl)-1-(4-methylbenzyl)pyrrolidin-2-one (BMS-986169), a Novel, Intravenous, Glutamate N-Methyl-d-Aspartate 2B Receptor Negative Allosteric Modulator with Potential in Major Depressive Disorder., Bristow LJ, Gulia J, Weed MR, Srikumar BN, Li YW, Graef JD, Naidu PS, Sanmathi C, Aher J, Bastia T, Paschapur M, Kalidindi N, Kumar KV, Molski T, Pieschl R, Fernandes A, Brown JM, Sivarao DV, Newberry K, Bookbinder M, Polino J, Keavy D, Newton A, Shields E, Simmermacher J, Kempson J, Li J, Zhang H, Mathur A, Kallem RR, Sinha M, Ramarao M, Vikramadithyan RK, Thangathirupathy S, Warrier J, Islam I, Bronson JJ, Olson RE, Macor JE, Albright CF, King D, Thompson LA, Marcin LR, Sinz M., J Pharmacol Exp Ther. December 1, 2017; 363 (3): 377-393.
Pomegranate juice, but not an extract, confers a lower glycemic response on a high-glycemic index food: randomized, crossover, controlled trials in healthy subjects., Kerimi A, Nyambe-Silavwe H, Gauer JS, Tomás-Barberán FA, Williamson G., Am J Clin Nutr. December 1, 2017; 106 (6): 1384-1393.
Phenylalanine derivatives with modulating effects on human α1-glycine receptors and anticonvulsant activity in strychnine-induced seizure model in male adult rats., Sadek B, Oz M, Nurulain SM, Jayaprakash P, Latacz G, Kieć-Kononowicz K, Szymańska E., Epilepsy Res. December 1, 2017; 138 124-131.
PFKFB4 control of AKT signaling is essential for premigratory and migratory neural crest formation., Figueiredo AL, Maczkowiak F, Borday C, Pla P, Sittewelle M, Pegoraro C, Monsoro-Burq AH., Development. November 15, 2017; 144 (22): 4183-4194.
Phosphorylation Dynamics Dominate the Regulated Proteome during Early Xenopus Development., Peuchen EH, Cox OF, Sun L, Hebert AS, Coon JJ, Champion MM, Dovichi NJ, Huber PW., Sci Rep. November 15, 2017; 7 (1): 15647.
PIP2 mediates functional coupling and pharmacology of neuronal KCNQ channels., Kim RY, Pless SA, Kurata HT., Proc Natl Acad Sci U S A. November 7, 2017; 114 (45): E9702-E9711.
Protein kinase C enhances plasma membrane expression of cardiac L-type calcium channel, CaV1.2., Raifman TK, Kumar P, Haase H, Klussmann E, Dascal N, Weiss S., Channels (Austin). November 2, 2017; 11 (6): 604-615.
Peptidomic analysis of skin secretions of the Mexican burrowing toad Rhinophrynus dorsalis (Rhinophrynidae): Insight into the origin of host-defense peptides within the Pipidae and characterization of a proline-arginine-rich peptide., Conlon JM, Guilhaudis L, Leprince J, Coquet L, Mangoni ML, Attoub S, Jouenne T, King JD., Peptides. November 1, 2017; 97 22-28.
Protein phosphatase 1 and phosphatase 1 nuclear targeting subunit-dependent regulation of DNA-dependent protein kinase and non-homologous end joining., Zhu S, Fisher LA, Bessho T, Peng A., Nucleic Acids Res. October 13, 2017; 45 (18): 10583-10594.
Pro-arrhythmogenic Effects of the V141M KCNQ1 Mutation in Short QT Syndrome and Its Potential Therapeutic Targets: Insights from Modeling., Rudy Y, Liang H, Chen CC, Luo CH, Sheu SH, Cui J., J Med Biol Eng. October 1, 2017; 37 (5): 780-789.
Protection against mosquito vectors Aedes aegypti, Anopheles stephensi and Culex quinquefasciatus using a novel insect repellent, ethyl anthranilate., Islam J, Zaman K, Tyagi V, Duarah S, Dhiman S, Chattopadhyay P., Acta Trop. October 1, 2017; 174 56-63.
Pharmacological modulation of Acid-Sensing Ion Channels 1a and 3 by amiloride and 2-guanidine-4-methylquinazoline (GMQ)., Besson T, Lingueglia E, Salinas M., Neuropharmacology. October 1, 2017; 125 429-440.
Promotora assisted depression and self-care management among predominantly Latinos with concurrent chronic illness: Safety net care system clinical trial results., Ell K, Aranda MP, Wu S, Oh H, Lee PJ, Guterman J., Contemp Clin Trials. October 1, 2017; 61 1-9.
Post-translational palmitoylation controls the voltage gating and lipid raft association of the CALHM1 channel., Taruno A, Sun H, Nakajo K, Murakami T, Ohsaki Y, Kido MA, Ono F, Marunaka Y., J Physiol. September 15, 2017; 595 (18): 6121-6145.
Pharmacological characterisation of S 47445, a novel positive allosteric modulator of AMPA receptors., Bretin S, Louis C, Seguin L, Wagner S, Thomas JY, Challal S, Rogez N, Albinet K, Iop F, Villain N, Bertrand S, Krazem A, Bérachochéa D, Billiald S, Tordjman C, Cordi A, Bertrand D, Lestage P, Danober L., PLoS One. September 8, 2017; 12 (9): e0184429.
Prdm13 forms a feedback loop with Ptf1a and is required for glycinergic amacrine cell genesis in the Xenopus Retina., Bessodes N, Parain K, Bronchain O, Bellefroid EJ, Perron M., Neural Dev. September 1, 2017; 12 (1): 16.
Peroxiredoxin1, a novel regulator of pronephros development, influences retinoic acid and Wnt signaling by controlling ROS levels., Chae S, Kim YK, Jung Sim H, Ji Y, Kim C, Ismail T, Park JW, Kwon OS, Kang BS, Lee DS, Bae JS, Kim SH, Min KJ, Kyu Kwon T, Park MJ, Han JK, Kwon T, Park TJ, Lee HS., Sci Rep. August 21, 2017; 7 (1): 8874.
Photoswitchable Inhibitor of a Glutamate Transporter., Cheng B, Shchepakin D, Kavanaugh MP, Trauner D., ACS Chem Neurosci. August 16, 2017; 8 (8): 1668-1672.
Polycomb repressive complex 2 in an autoinhibited state., Bratkowski M, Yang X, Liu X., J Biol Chem. August 11, 2017; 292 (32): 13323-13332.
Pax2/Pax8-defined subdomains and the occurrence of apoptosis in the posterior placodal area of mice., Washausen S, Knabe W., Brain Struct Funct. August 1, 2017; 222 (6): 2671-2695.
Possible roles of mechanical cell elimination intrinsic to growing tissues from the perspective of tissue growth efficiency and homeostasis., Lee SW, Morishita Y., PLoS Comput Biol. July 13, 2017; 13 (7): e1005651.
Population-Specific Resequencing Associates the ATP-Binding Cassette Subfamily C Member 4 Gene With Gout in New Zealand Māori and Pacific Men., Tanner C, Boocock J, Stahl EA, Dobbyn A, Mandal AK, Cadzow M, Phipps-Green AJ, Topless RK, Hindmarsh JH, Stamp LK, Dalbeth N, Choi HK, Mount DB, Merriman TR., Arthritis Rheumatol. July 1, 2017; 69 (7): 1461-1469.
Pharmacology of the Nav1.1 domain IV voltage sensor reveals coupling between inactivation gating processes., Osteen JD, Sampson K, Iyer V, Julius D, Bosmans F., Proc Natl Acad Sci U S A. June 27, 2017; 114 (26): 6836-6841.
Probing the Structural Dynamics of the NMDA Receptor Activation by Coarse-Grained Modeling., Zheng W, Wen H, Iacobucci GJ, Popescu GK., Biophys J. June 20, 2017; 112 (12): 2589-2601.
Paxillin and embryonic PolyAdenylation Binding Protein (ePABP) engage to regulate androgen-dependent Xenopus laevis oocyte maturation - A model of kinase-dependent regulation of protein expression., Miedlich SU, Taya M, Young MR, Hammes SR., Mol Cell Endocrinol. June 15, 2017; 448 87-97.
Plk1 Phosphorylation of Mre11 Antagonizes the DNA Damage Response., Li Z, Li J, Kong Y, Yan S, Ahmad N, Liu X., Cancer Res. June 15, 2017; 77 (12): 3169-3180.
PTK7 localization and protein stability is affected by canonical Wnt ligands., Berger H, Breuer M, Peradziryi H, Podleschny M, Jacob R, Borchers A., J Cell Sci. June 1, 2017; 130 (11): 1890-1903.
Photoaffinity Ligand for the Inhalational Anesthetic Sevoflurane Allows Mechanistic Insight into Potassium Channel Modulation., Woll KA, Peng W, Liang Q, Zhi L, Jacobs JA, Maciunas L, Bhanu N, Garcia BA, Covarrubias M, Loll PJ, Dailey WP, Eckenhoff RG., ACS Chem Biol. May 19, 2017; 12 (5): 1353-1362.
Protein kinase A regulates C-terminally truncated CaV 1.2 in Xenopus oocytes: roles of N- and C-termini of the α1C subunit., Oz S, Pankonien I, Belkacemi A, Flockerzi V, Klussmann E, Haase H, Dascal N., J Physiol. May 15, 2017; 595 (10): 3181-3202.
PKC-mediated phosphorylation of nuclear lamins at a single serine residue regulates interphase nuclear size in Xenopus and mammalian cells., Edens LJ, Dilsaver MR, Levy DL., Mol Biol Cell. May 15, 2017; 28 (10): 1389-1399.
Pharmacological characterization of histamine-gated chloride channels from the housefly Musca domestica., Kita T, Irie T, Nomura K, Ozoe F, Ozoe Y., Neurotoxicology. May 1, 2017; 60 245-253.
Pharmacological characterization of the excitatory 'Cys-loop' GABA receptor family in Caenorhabditis elegans., Nicholl GC, Jawad AK, Weymouth R, Zhang H, Beg AA., Br J Pharmacol. May 1, 2017; 174 (9): 781-795.
Probing for and Quantifying Agonist Hydrogen Bonds in α6β2 Nicotinic Acetylcholine Receptors., Post MR, Lester HA, Dougherty DA., Biochemistry. April 4, 2017; 56 (13): 1836-1840.
Polar Localization of the NIP5;1 Boric Acid Channel Is Maintained by Endocytosis and Facilitates Boron Transport in Arabidopsis Roots., Wang S, Yoshinari A, Shimada T, Hara-Nishimura I, Mitani-Ueno N, Feng Ma J, Naito S, Takano J., Plant Cell. April 1, 2017; 29 (4): 824-842.
Post-stimulation block of frog sciatic nerve by high-frequency (kHz) biphasic stimulation., Yang G, Xiao Z, Wang J, Shen B, Roppolo JR, de Groat WC, Tai C., Med Biol Eng Comput. April 1, 2017; 55 (4): 585-593.
Pattern of Neurogenesis and Identification of Neuronal Progenitor Subtypes during Pallial Development in Xenopus laevis., Moreno N, González A., Front Neuroanat. March 27, 2017; 11 24.
Pentameric ligand-gated ion channels exhibit distinct transmembrane domain archetypes for folding/expression and function., Therien JP, Baenziger JE., Sci Rep. March 27, 2017; 7 (1): 450.
Probing the Structural Mechanism of Partial Agonism in Glycine Receptors Using the Fluorescent Artificial Amino Acid, ANAP., Soh MS, Estrada-Mondragon A, Durisic N, Keramidas A, Lynch JW., ACS Chem Biol. March 17, 2017; 12 (3): 805-813.
Post-translational cleavage of Hv1 in human sperm tunes pH- and voltage-dependent gating., Berger TK, Fußhöller DM, Goodwin N, Bönigk W, Müller A, Dokani Khesroshahi N, Brenker C, Wachten D, Krause E, Kaupp UB, Strünker T., J Physiol. March 1, 2017; 595 (5): 1533-1546.
Preclinical development of moxidectin as a novel therapeutic for alcohol use disorder., Huynh N, Arabian N, Naito A, Louie S, Jakowec MW, Asatryan L, Davies DL., Neuropharmacology. February 1, 2017; 113 (Pt A): 60-70.
Primary Brain Calcification Causal PiT2 Transport-Knockout Variants can Exert Dominant Negative Effects on Wild-Type PiT2 Transport Function in Mammalian Cells., Larsen FT, Jensen N, Autzen JK, Kongsfelt IB, Pedersen L., J Mol Neurosci. February 1, 2017; 61 (2): 215-220.
Pth4, an ancient parathyroid hormone lost in eutherian mammals, reveals a new brain-to-bone signaling pathway., Suarez-Bregua P, Torres-Nuñez E, Saxena A, Guerreiro P, Braasch I, Prober DA, Moran P, Cerda-Reverter JM, Du SJ, Adrio F, Power DM, Canario AV, Postlethwait JH, Bronner ME, Cañestro C, Rotllant J., FASEB J. February 1, 2017; 31 (2): 569-583.
Pa2G4 is a novel Six1 co-factor that is required for neural crest and otic development., Neilson KM, Abbruzzesse G, Kenyon K, Bartolo V, Krohn P, Alfandari D, Moody SA., Dev Biol. January 15, 2017; 421 (2): 171-182.
Primordial Germ Cell Isolation from Xenopus laevis Embryos., Butler AM, Aguero T, Newman KM, King ML., Methods Mol Biol. January 1, 2017; 1463 115-124.

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